Reseach Interests

Retrotransposons, Genomics, Bioinformatics, Combination of Imaging and Sequencing Methods

Education

Ph.D. in Basic Medicine
School of Medicine
Advisor: Prof. Xiaohua Shen
Tsinghua University, 2013-2021
Visiting Student
Institute of Crop Sciences
Advisor: Prof. Cunxiang Wu
Chinese Academy of Agricultural Sciences, 2012-2013
B.S. in Bioengineering
School of Life Sciences
Advisor: Prof. Yongjun Feng
Beijing Institute of Technology, 2009-2013

Experience

Postdoctoral scholar
School of Medicine
Advisor: Prof. Xiaohua Shen
Tsinghua University, 2021-2024

Publications

Also see my Google Scholar Profile.

 
Phase separation of RNA-binding protein promotes polymerase binding and transcription
Shao, W., Bi, X., Pan, Y., Gao, B., ... Zhan, G., ..., Shen, X.#
Nature Chemical Biology, 2022 [Paper]
 
Homotypic clustering of L1 and B1/Alu repeats compartmentalizes the 3D genome
Lu, J. Y., Chang, L., Li, T., Wang, T.*, Yin, Y.*, Zhan, G.*, ..., Shen, X.#
Cell Research, 2021 [Paper]
 
RNA Targets Ribogenesis Factor WDR43 to Chromatin for Transcription and Pluripotency Control
Bi, X., Xu, Y.*, Li, T. *, Li, X. *, Li, W. *, Shao, W. *, Wang, K. *, Zhan, G. *, ..., Shen, X.#
Molecular Cell, 2019 [Paper]
 
Analysis of C. elegans muscle transcriptome using trans-splicing-based RNA tagging (SRT)
Ma, X.*, Zhan, G.*, Sleumer, M. C., Chen, S., Liu, W., Zhang, M. Q., Liu, X.#
Nucleic Acids Research, 2016 [Paper]

Awards

  • Outstanding Flash Talk, Epigenetics and Chromatin Biology Conference, Wuhan, China, 2023.
  • Outstanding Postdoctoral Fund, Center for Life Science ($3282), 2022-2024.
  • Outstanding Poster Prize in Ph.D. Forum, Tsinghua University, 2021.

Technical Skills

Programming & Libraries

AlphaFold at LNS Group

Software

Systems

Wet Lab

Molecular Clone, Cell Culture, ATAC-seq, Smart-seq2, mRNA Display, Mutagenesis, CRISPR Knockout, CRISPR Knockin, CRISPR Screen, Lentivirus, etc.